Project P08
Gene regulation

Pernilla Stridh

Pernilla Stridh is Senior Researcher and Team Leader of Functional Genomics of Neurodegeneration and Inflammation at the Department of Clinical Neuroscience, Karolinska Institutet in Stockholm, Sweden. Her research strives to understand how genetic drivers of neuroinflammation modifies neurodegeneration and disease progression in Multiple Sclerosis. This builds on her expertise in genetics acquired through her PhD at Department of Clinical Neuroscience (2005-2010), functional genomics during her postdoc at Karolinska Institutet (2011-2015), and sequence-based genetic analysis during her short-term fellowship at University of Oxford, United Kingdom (2012). In 2015, she was appointed Assistant Professor in Experimental and Human Genetics of Neuroinflammatory Disease for her expertise in advanced genetic association and mediation analyses, further fostered during several research visits at deCODE Genetics in Iceland (2017, 2019). Her team utilizes innovative genome-wide and sequence-based approaches combined with large registry linkage to identify and characterize mechanisms that accelerate neurodegeneration, to identify treatment strategies that promote resilience and halt disease. Her outstanding scientific quality and leadership is recognized by multiple awards, fellowships and grants (e.g. Frithiof Lennmalms Prize and Silver Medal and Margaretha af Ugglas Foundation grant). Her focus within Neuroflame is to identify candidate genes driving neurodegeneration and test functional pathways in MS progression.